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OCR: James E Griffin MD Professor of Internal Medicine The University of Texas Southwestern Medical Center Department of Internal Medicine Dallas, Texas, USA Reginald Hall CBE, MD, FRCP Professor of Medicine Emeritus University of Wales College of Medicine Cardiff, UK Peter Hammond MD, MA, MRCP Division of Endocrinology & Metabolism Department of Medicine Hammersmith Hospital London, UK Victor M. Haughton MD Professor of Radiology Director of Neuroradiology Research Medical College of Wisconsin Froedtert Memorial Lutheran Hospital Milwaukee, Wisconsin, USA